Reshmi Buthello is Head of People & Culture at Main Sequence and 5B, where she supports novel tech ventures through scale, maturity, and culture building. With global experience across large tech and early-stage companies, Reshmi brings strategic clarity, talent insight, and an investor mindset to her People practice. She’s passionate about helping teams build the internal capability and leadership edge that growth demands.
What makes a company truly investable? In this panel, Melanie Robb, Erika Enberg, Jess Blomfield, and Reshmi Buthello bring investor and operator perspectives to the people, culture, and leadership traits that signal growth readiness. Reshmi draws from her experience with deep tech scale-ups at Main Sequence and 5B; Erika from nearly two decades guiding startups from seed to Series E; Jess from her work with ANZ's leading startups at Airtree Ventures; and Melanie from advising early-stage founders through her people-first, scale-ready frameworks at avviare. Together, they’ll explore the fundamentals investors notice, the red flags they don’t ignore, and how People leaders can align talent, culture, and strategy for long-term success. This is for anyone building from the inside—and thinking like an investor.
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